Skip to content Skip to sidebar Skip to footer

(DOWNLOAD) "Heteroaromatic Lipoxin A4 Analogues" by Colm Duffy # eBook PDF Kindle ePub Free

Heteroaromatic Lipoxin A4 Analogues

📘 Read Now     📥 Download


eBook details

  • Title: Heteroaromatic Lipoxin A4 Analogues
  • Author : Colm Duffy
  • Release Date : January 10, 2012
  • Genre: Chemistry,Books,Science & Nature,Life Sciences,
  • Pages : * pages
  • Size : 2243 KB

Description

In this thesis Colm Duffy reviews the chemistry and biology of stable lipoxin analogues. Colm has prepared for the first time ever a pyridine-containing LXA4 analogue in enantiomerically pure form. Biological evaluation determined that both epimers at the benzylic position suppress key cytokines known to be involved in inflammatory disease, with the (R)-epimer proving most efficacious. Moreover the author developed an excellent route to a related thiophene-containing analogue that also showed interesting biological activity. Both routes have inspired further work in  the synthesis of further heteroaromatic analogues for biological evaluation.


Free PDF Download "Heteroaromatic Lipoxin A4 Analogues" Online ePub Kindle